Molecular Hydrogen

Oxygen and hydrogen provide a balance between oxidation and reduction, to get mitochondrial ATP energy, which is vital for life. Molecular hydrogen is able to protect cell membranes by trapping the highly toxic hydroxyl radical. Hydrogen indirectly affects the expression of genes through its actions to modulate molecules that have an epigenetic effect, molecular hydrogen can modulate inflammatory responses and apoptosis through NF-kB and TNFa. 383 Scientific studies of molecular hydrogen in English: Hydrogen in Biomedicine www.molecularhydrogenstudies.com   (2018)

The evolution of molecular hydrogen: a noteworthy potential therapy with clinical significance medicalgasresearch.biomedcentral.com/articles/10.1186/2045-9912-3-10   (2014).

Beneficial biological effects and the underlying molecular hydrogen mechanisms - comprehensive review of 321 original articles. medicalgasresearch.biomedcentral.com/articles/10.1186/s13618-015-0035-..   (2016).

The molecular hydrogen is introduced into the cells and protect our DNA and our genes, so that the mitochondria produce the energy necessary for growth, repair and regeneration of the body, improving our longevity. The molecular hydrogen is 80 times smaller than the vitamin C, this provides great capacity of hydration to the hydrogenated water, and great power to the hydrogen to cross the blood-brain barrier. Studies have shown that hydrogen exerts antioxidant, antiapoptotic, anti-inflammatory and cytoprotective properties that are beneficial for the cell, preventing chronic and neurodegenerative diseases. It increases the levels of superoxide dismutase and glutathione as well as the Nef2 diet. Hydrogen also prevents the oxidation of proteins and fats. Hydrogenated water has a hexagonal molecular structure of small molecular size, with a negative reduction oxidation potential (-100 to -900mV), with a very antioxidant effect. The more negative the value, the greater the antioxidant capacity.

From 2007 to 2016 numerous articles have been published that have shown that the effects can be mediated by the modulation of activities and expressions of various molecules such as Lyn, ERK, p38, JNK, ASK1, Akt, GTP-Rac1, iNOS, Nox1, NF -kB p65, I?B?, STAT3, NFATc1 and c-Fos, which are related to chronic and degenerative diseases. The consumption of water in dissolved hydrogen seems to improve the pathology of mitochondrial disorders. Drinking H2-water stimulates energy metabolism, measured by O2 consumption and CO2 production. Molecular hydrogen Institute www.molecularhydrogeninstitute.com   (2018).-

Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators www.ncbi.nlm.nih.gov/.../PMC4704061   (2016).-

Molecular hydrogen is a novel antioxidant to reduce oxidative stress with potential for the improvement of mitochondrial diseases www.medicinabiomolecular.com.br/biblioteca/pdfs/Biomolecular/mb-0318.p..  (2015).-

These review articles seek to deepen and thoroughly analyze the research and experiments that allude to molecular hydrogen as a novel therapeutic treatment. Molecular hydrogen: a preventive and therapeutic medical gas for various diseases www.ncbi.nlm.nih.gov/.../PMC5731988  (2017).-

Molecular hydrogen: simple preventive measures in the fight against cancer and degenerative diseases. www.cancertutor.com/molecular-hydrogen-preventive-health  (2017).-

Antidiabetics www.waterfyi.com/uncategorized/13-of-americans-are-diabetic-or-prediab..  (2018).-  pdfs.semanticscholar.org/749b/81ecf01007075a8665665fa97d9cecbc16f8.pdf  (2013). www.ncbi.nlm.nih.gov/.../19083400  (2008).-

Improve cognitive function and against Alzheimers www.ncbi.nlm.nih.gov/.../29683360  (2018). www.waterfyi.com/.../alzheimers-and-h2-molecular-hydrogen  (2018).- alkaway.com/blog/can-molecular-hydrogen-help-alzheimers-dementia/  (2017).-

It has anti-cancer effects: it suppresses VEGF (Vascular Endothelial Growth Factor), a key mediator of tumor angiogenesis, reduces excessive expressions of MMP genes, which lead to tumor invasion, shorten telomeres in cancer cells, increased expression of p -AMPK, AIF and caspase 3, pathways of apoptosis of cancer cells and other routes exposed in these links. www.cancertutor.com/hydrogen-water-cancer  (2017).- www.ncbi.nlm.nih.gov/.../PMC4464386  (2015). www.ncbi.nlm.nih.gov/.../PMC3386386  (2014) www.ncbi.nlm.nih.gov/.../19192719  (2009). www.ncbi.nlm.nih.gov/.../27438130  (2016).-

Molecular hydrogen in allergic diseases image.sciencenet.cn/olddata/kexue.com.cn/upload/blog/file/2009/9/20099..  (2016).-

The results of increased iron and lipid peroxidation and reduced levels of reduced glutathione in the brain indicate that oxidative stress is involved in the pathogenesis of Parkinson's disease (PD). In addition, endogenous H 2 may be closely related to the pathogenesis of EP because environmental toxins damaged intrinsic melanin, and H2 prevents its deterioration.

Pilot study of H? therapy in Parkinson's disease: a randomized double-blind placebo-controlled trial. www.ncbi.nlm.nih.gov/.../23400965  (2014).-

A randomized double-blind multi-center trial of hydrogen water for Parkinson’s disease: protocol and baseline characteristics www.ncbi.nlm.nih.gov/.../PMC4865993  (2016).-

A randomized double-blind, placebo-controlled multi-center trial of molecular hydrogen water for Parkinson’s disease www.jns-journal.com/.../S0022-510X  (17)33469-X/fulltext (2017).-

Improve cognitive function and against Alzheimers www.ncbi.nlm.nih.gov/.../29683360  (2018). www.waterfyi.com/.../alzheimers-and-h2-molecular-hydrogen  (2018).- alkaway.com/blog/can-molecular-hydrogen-help-alzheimers-dementia/  (2017).-

It has anti-cancer effects: it suppresses VEGF (Vascular Endothelial Growth Factor), a key mediator of tumor angiogenesis, reduces excessive expressions of MMP genes, which lead to tumor invasion, shorten telomeres in cancer cells, increased expression of p -AMPK, AIF and caspase 3, pathways of apoptosis of cancer cells and other routes exposed in these links. www.cancertutor.com/hydrogen-water-cancer  (2017).- www.ncbi.nlm.nih.gov/.../PMC4464386  (2015). www.ncbi.nlm.nih.gov/.../PMC3386386  (2014) www.ncbi.nlm.nih.gov/.../19192719  (2009). www.ncbi.nlm.nih.gov/.../27438130  (2016).-

Molecular hydrogen in allergic diseases image.sciencenet.cn/olddata/kexue.com.cn/upload/blog/file/2009/9/20099..  (2016).-

The results of increased iron and lipid peroxidation and reduced levels of reduced glutathione in the brain indicate that oxidative stress is involved in the pathogenesis of Parkinson's disease (PD). In addition, endogenous H 2 may be closely related to the pathogenesis of EP because environmental toxins damaged intrinsic melanin, and H2 prevents its deterioration.

Pilot study of H? therapy in Parkinson's disease: a randomized double-blind placebo-controlled trial. www.ncbi.nlm.nih.gov/.../23400965  (2014).-

A randomized double-blind multi-center trial of hydrogen water for Parkinson’s disease: protocol and baseline characteristics www.ncbi.nlm.nih.gov/.../PMC4865993  (2016).-

A randomized double-blind, placebo-controlled multi-center trial of molecular hydrogen water for Parkinson’s disease www.jns-journal.com/.../S0022-510X  (17)33469-X/fulltext (2017).-


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